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Literature summary extracted from

  • Sabbagh, G.; Berakdar, N.
    Molecular docking study of flavonoid compounds as inhibitors of beta-ketoacyl acyl carrier protein synthase II (KAS II) of Pseudomonas aeruginosa (2016), Int. J. Pharm. Pharm. Sci., 8, 52-61 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.179 3-benzamido-2-hydroxybenzoic acid
-
 Pseudomonas aeruginosa
2.3.1.179 casticin i.e. 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.179 a (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] Pseudomonas aeruginosa
-
 a (Z)-3-oxooctadeca-11-enoyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]
-
 ?
2.3.1.179 a (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] Pseudomonas aeruginosa ATCC 15692
-
 a (Z)-3-oxooctadeca-11-enoyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.179 Pseudomonas aeruginosa G3XDA2
-
-
2.3.1.179 Pseudomonas aeruginosa ATCC 15692 G3XDA2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.179 a (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein]
-
 Pseudomonas aeruginosa a (Z)-3-oxooctadeca-11-enoyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]
-
 ?
2.3.1.179 a (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein]
-
 Pseudomonas aeruginosa ATCC 15692 a (Z)-3-oxooctadeca-11-enoyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.179 beta-ketoacyl acyl carrier protein synthase II
-
 Pseudomonas aeruginosa
2.3.1.179 FabF
-
 Pseudomonas aeruginosa
2.3.1.179 KAS II
-
 Pseudomonas aeruginosa