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Literature summary extracted from

  • Dominguez, C.V.; Maestro, J.L.
    Expression of juvenile hormone acid O-methyltransferase and juvenile hormone synthesis in Blattella germanica (2018), Insect Sci., 25, 787-796 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.325
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 Blattella germanica

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.325 Blattella germanica A0A2C8C2A6
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.325 corpus allatum the enzyme is mainly expressed in corpora allata, with only expression traces in ovary. Three different isoforms, differing in the 3'-UTR sequence, are identified. Isoform A shows between 35 and 65 times higher expression than B and C in corpora allata from penultimate nymphal instar and adult females Blattella germanica
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2.1.1.325 ovary the enzyme is mainly expressed in corpora allata, with only expression traces in ovary Blattella germanica
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Synonyms

EC Number Synonyms Comment Organism
2.1.1.325 JHAMT
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 Blattella germanica
2.1.1.325 juvenile hormone acid-methyltransferase
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 Blattella germanica

Expression

EC Number Organism Comment Expression
2.1.1.325 Blattella germanica mRNA levels are reduced in starved females and in females in which nutritional signaling is reduced by knocking down insulin receptor and target of rapamycin down

General Information

EC Number General Information Comment Organism
2.1.1.325 malfunction RNAi-triggered knock down of the enzyme (JHAMT) produces an extremely high reduction of synthesis of the juvenile hormone, concomitant with a decrease of fat body vitellogenin expression and basal follicle length Blattella germanica
2.1.1.325 physiological function nutrition and its signaling through the insulin receptor and TOR pathways are essential for activating enzyme (JHAMT) expression, which suggests that this enzyme can be a checkpoint for the regulation of juvenile hormone production in relation to nutritional status Blattella germanica