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Literature summary extracted from

  • Noh, M.Y.; Koo, B.; Kramer, K.J.; Muthukrishnan, S.; Arakane, Y.
    Arylalkylamine N-acetyltransferase 1 gene (TcAANAT1) is required for cuticle morphology and pigmentation of the adult red flour beetle, Tribolium castaneum (2016), Insect Biochem. Mol. Biol., 79, 119-129 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.87 expression in Escherichia coli Tribolium castaneum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.87 0.05
-
norepinephrine pH not specified in the publication, temperature not specified in the publication Tribolium castaneum
2.3.1.87 0.07
-
octopamine pH not specified in the publication, temperature not specified in the publication Tribolium castaneum
2.3.1.87 0.1
-
tryptamine pH not specified in the publication, temperature not specified in the publication Tribolium castaneum
2.3.1.87 0.11
-
dopamine pH not specified in the publication, temperature not specified in the publication Tribolium castaneum
2.3.1.87 0.56
-
tyramine pH not specified in the publication, temperature not specified in the publication Tribolium castaneum

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.87 Tribolium castaneum A0A1J0AHX8
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.87 acetyl-CoA + dopamine
-
Tribolium castaneum CoA + N-acetyldopamine
-
?
2.3.1.87 acetyl-CoA + norepinephrine
-
Tribolium castaneum CoA + N-acetylnorepinephrine
-
?
2.3.1.87 acetyl-CoA + octopamine
-
Tribolium castaneum CoA + N-acetyloctopamine
-
?
2.3.1.87 acetyl-CoA + tryptamine
-
Tribolium castaneum CoA + N-acetyltryptamine
-
?
2.3.1.87 acetyl-CoA + tyramine
-
Tribolium castaneum CoA + N-acetyltyramine
-
?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.87 AANAT1
-
Tribolium castaneum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.87 7.5 8.5 substrate dopamine Tribolium castaneum

Expression

EC Number Organism Comment Expression
2.3.1.87 Tribolium castaneum transcripts are detected at all stages of development with lowest expressions at the embryonic and pharate pupal stages additional information

General Information

EC Number General Information Comment Organism
2.3.1.87 physiological function loss of function of AANAT1 caused by RNAi has no effect on larval and pupal development. The tanning of pupal setae, gin traps and urogomphi proceeds normally. About 70% of the resulting adults exhibit a roughened exoskeletal surface, separated elytra and improperly folded hindwings. The body wall, elytra and veins of the hindwing of the mature adults are significantly darker than those of control insects probably due to the accumulation of dopamine melanin Tribolium castaneum