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Literature summary extracted from

  • Patil, K.; Wakkar, L.; Undare, S.; Kolekar, G.; Deshmukh, M.; Choudhari, P.; Anbhule, P.
    Selective synthesis of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione using copper oxide nanoparticles for potential inhibitors of beta-ketoacyl-[acyl-carrier-protein] synthase III of Mycobacterium tuberculosis (2016), Indian J. Chem., 55B, 1151-1159.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.180 10,10-dimethyl-7-(2-nitrophenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
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Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(3-chlorophenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(3-nitrophenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(4-chlorophenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(4-hydroxy-3-methoxyphenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(4-hydroxyphenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(4-nitrophenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(naphthalen-2-yl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis
2.3.1.180 10,10-dimethyl-7-(thiophen-2-yl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione
-
Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.180 Mycobacterium tuberculosis
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-
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2.3.1.180 Mycobacterium tuberculosis H37Rv
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-
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.180 beta-ketoacyl-[acyl-carrier-protein] synthase III
-
Mycobacterium tuberculosis
2.3.1.180 FabH
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Mycobacterium tuberculosis