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Literature summary extracted from

  • Tao, T.; Chen, Q.; Meng, X.; Yan, J.; Xu, F.; Chang, J.
    Molecular cloning, characterization, and functional analysis of a gene encoding 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Matricaria chamomilla (2016), Genes Genomics, 38, 1179-1187 .
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.3.10
-
 Matricaria chamomilla

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.3.10 50700
-
 calculated from sequence Matricaria chamomilla

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.3.10 acetyl-CoA + H2O + acetoacetyl-CoA Matricaria chamomilla first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.10 Matricaria chamomilla A0A140GL77
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.3.10 flower predominantly expressed in flowers Matricaria chamomilla
-
2.3.3.10 leaf
-
 Matricaria chamomilla
-
2.3.3.10 root
-
 Matricaria chamomilla
-
2.3.3.10 stem
-
 Matricaria chamomilla
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.3.10 acetyl-CoA + H2O + acetoacetyl-CoA
-
 Matricaria chamomilla (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
2.3.3.10 acetyl-CoA + H2O + acetoacetyl-CoA first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla Matricaria chamomilla (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.3.10 3-hydroxy-3-methylglutaryl-coenzyme A synthase
-
 Matricaria chamomilla
2.3.3.10 HMGS
-
 Matricaria chamomilla

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.3.3.10 Matricaria chamomilla calculated from sequence
-
 5.69

Expression

EC Number Organism Comment Expression
2.3.3.10 Matricaria chamomilla induced by methyl jasmonate. The transcript level increases gradually and reaches maximum (5.6fold higher than the control) at 24 h after methyl jasmonate treatment. Thereafter, the transcript level declines but is still significant higher than those of control from 48 to 96 h posttreatment of methyl jasmonate. At 96 h, a 2.4fold increase in expression compared to control is observed up

General Information

EC Number General Information Comment Organism
2.3.3.10 metabolism first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla Matricaria chamomilla