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Literature summary extracted from

  • Neumann, E.; Mehboob, H.; Ramํrez, J.; Mirkov, S.; Zhang, M.; Liu, W.
    Age-dependent hepatic UDP-glucuronosyltransferase gene expression and activity in children (2016), Front. Pharmacol., 7, 437 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Homo sapiens O60656
-
-
2.4.1.17 Homo sapiens O75795
-
-
2.4.1.17 Homo sapiens P06133
-
-
2.4.1.17 Homo sapiens P16662
-
-
2.4.1.17 Homo sapiens P19224
-
-
2.4.1.17 Homo sapiens P22309
-
-
2.4.1.17 Homo sapiens P22310
-
-
2.4.1.17 Homo sapiens P35503
-
-
2.4.1.17 Homo sapiens P35504
-
-
2.4.1.17 Homo sapiens P36537
-
-
2.4.1.17 Homo sapiens P54855
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 (S)-oxazepam + UDP-glucuronate
-
 Homo sapiens UDP + (S)-oxazepam beta-D-glucuronoside
-
 ?
2.4.1.17 acetaminophen + UDP-glucuronate
-
 Homo sapiens UDP + ?
-
 ?
2.4.1.17 anastrozole + UDP-glucuronate
-
 Homo sapiens UDP + ?
-
 ?
2.4.1.17 bilirubin + UDP-glucuronate
-
 Homo sapiens UDP + bilirubin-glucuronoside
-
 ?
2.4.1.17 epirubicin + UDP-glucuronate
-
 Homo sapiens UDP + epirubicin beta-D-glucuronoside
-
 ?
2.4.1.17 flavopiridol + UDP-glucuronate
-
 Homo sapiens UDP + flavopiridol beta-D-glucuronoside
-
 ?
2.4.1.17 imipramine + UDP-glucuronate
-
 Homo sapiens UDP + ?
-
 ?
2.4.1.17 morphine + UDP-glucuronate
-
 Homo sapiens UDP + morphine 3-beta-D-glucuronoside
-
 ?
2.4.1.17 mycophenolic acid + UDP-glucuronate
-
 Homo sapiens UDP + mycophenolic acid beta-D-glucuronoside
-
 ?
2.4.1.17 serotonin + UDP-glucuronate
-
 Homo sapiens UDP + serotonin beta-D-glucuronide
-
 ?
2.4.1.17 SN-38 + UDP-glucuronate
-
 Homo sapiens UDP + 7-ethyl-10-hydroxycamptothecin 10-O-beta-D-glucuronoside
-
 ?
2.4.1.17 testosterone + UDP-glucuronate
-
 Homo sapiens UDP + testosterone beta-D-glucuronoside
-
 ?
2.4.1.17 thyroxine + UDP-glucuronate
-
 Homo sapiens UDP + thyroxine beta-D-glucuronoside
-
 ?
2.4.1.17 vorinostat + UDP-glucuronate
-
 Homo sapiens UDP + vorinostat beta-D-glucuronoside
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.17 UDP-glucuronosyltransferase
-
 Homo sapiens
2.4.1.17 UGT1A1 isoform Homo sapiens
2.4.1.17 UGT1A3 isoform Homo sapiens
2.4.1.17 UGT1A4 isoform Homo sapiens
2.4.1.17 UGT1A5 isoform Homo sapiens
2.4.1.17 UGT1A6 isoform Homo sapiens
2.4.1.17 UGT1A9 isoform Homo sapiens
2.4.1.17 UGT2B10 isoform Homo sapiens
2.4.1.17 UGT2B15 isoform Homo sapiens
2.4.1.17 UGT2B17 isoform Homo sapiens
2.4.1.17 UGT2B4 isoform Homo sapiens
2.4.1.17 UGT2B7 isoform Homo sapiens

Expression

EC Number Organism Comment Expression
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT1A1 during the first 25 years of life up
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT1A3 during the first 25 years of life up
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT1A4 during the first 25 years of life up
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT1A5 during the first 25 years of life up
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT1A6 during the first 25 years of life up
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT2B17 during the first 25 years of life up
2.4.1.17 Homo sapiens there is a significant increase in the expression of isoform UGT2B7 during the first 25 years of life up