EC Number | Cloned (Comment) | Organism |
---|---|---|
2.1.2.11 | expressed in Escherichia coli strain BW25113 or MG1655 | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.11 | 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O | Escherichia coli | - |
tetrahydrofolate + 2-dehydropantoate | - |
? | |
2.1.2.11 | 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O | Escherichia coli W3110 | - |
tetrahydrofolate + 2-dehydropantoate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.2.11 | Escherichia coli | - |
- |
- |
2.1.2.11 | Escherichia coli W3110 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.11 | 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O | - |
Escherichia coli | tetrahydrofolate + 2-dehydropantoate | - |
? | |
2.1.2.11 | 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O | - |
Escherichia coli W3110 | tetrahydrofolate + 2-dehydropantoate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.2.11 | ketopantoate hydroxymethyltransferase | - |
Escherichia coli |
2.1.2.11 | PanB | - |
Escherichia coli |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.1.2.11 | 5,10-methenyltetrahydrofolate | dependent on | Escherichia coli |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.1.2.11 | metabolism | enzyme overexpression leads to accumulation of the likely folate cleavage product 6-hydroxymethylpterin and other pterins in cells and medium, and to a 46% increase in total folate content | Escherichia coli |