Literature summary extracted from

Kerepesi, C.; Szabo, J.E.; Papp-Kadar, V.; Dobay, O.; Szabo, D.; Grolmusz, V.; Vertessy, B.G.
Life without dUTPase (2016), Front. Microbiol., 7, 1768 .

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.6.1.23	Stl protein	-	Aeromonas hydrophila
3.6.1.23	Stl protein	-	Campylobacter jejuni
3.6.1.23	Stl protein	-	Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.6.1.23	dUTP + H2O	Escherichia coli	-	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	Aeromonas hydrophila	-	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	Campylobacter jejuni	-	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	Aeromonas hydrophila ATCC 7966	-	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	Escherichia coli ATCC 25922	-	dUMP + diphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.6.1.23	Aeromonas hydrophila	-	-	-
3.6.1.23	Aeromonas hydrophila ATCC 7966	-	-	-
3.6.1.23	Campylobacter jejuni	-	-	-
3.6.1.23	Escherichia coli	-	-	-
3.6.1.23	Escherichia coli ATCC 25922	-	-	-
3.6.1.23	no activity in Staphylococcus aureus strain RN450	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.6.1.23	dUTP + H2O	-	Escherichia coli	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	-	Aeromonas hydrophila	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	-	Campylobacter jejuni	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	-	Aeromonas hydrophila ATCC 7966	dUMP + diphosphate	-	?
3.6.1.23	dUTP + H2O	-	Escherichia coli ATCC 25922	dUMP + diphosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.6.1.23	DUT	-	Escherichia coli
3.6.1.23	DUT	-	Aeromonas hydrophila
3.6.1.23	DUT	-	Campylobacter jejuni
3.6.1.23	dUTP pyrophosphatase	-	Escherichia coli
3.6.1.23	dUTP pyrophosphatase	-	Aeromonas hydrophila
3.6.1.23	dUTP pyrophosphatase	-	Campylobacter jejuni
3.6.1.23	dUTPase	-	Escherichia coli
3.6.1.23	dUTPase	-	Aeromonas hydrophila
3.6.1.23	dUTPase	-	Campylobacter jejuni

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)