Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhang, B.; Zhang, X.M.; Wang, W.; Liu, Z.Q.; Zheng, Y.G.
    Metabolic engineering of Escherichia coli for D-pantothenic acid production (2019), Food Chem., 294, 267-275 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.2.11 expressed in Escherichia coli W3110 cells Corynebacterium glutamicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.169 2-dehydropantoate + NADPH + H+ Escherichia coli
-
(R)-pantoate + NADP+
-
?
1.1.1.169 2-dehydropantoate + NADPH + H+ Escherichia coli W3110
-
(R)-pantoate + NADP+
-
?
2.1.2.11 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O Corynebacterium glutamicum
-
tetrahydrofolate + 2-dehydropantoate
-
?
2.1.2.11 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O Corynebacterium glutamicum ATCC 13032
-
tetrahydrofolate + 2-dehydropantoate
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.169 Escherichia coli
-
-
-
1.1.1.169 Escherichia coli W3110
-
-
-
2.1.2.11 Corynebacterium glutamicum
-
-
-
2.1.2.11 Corynebacterium glutamicum ATCC 13032
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.169 2-dehydropantoate + NADPH + H+
-
Escherichia coli (R)-pantoate + NADP+
-
?
1.1.1.169 2-dehydropantoate + NADPH + H+
-
Escherichia coli W3110 (R)-pantoate + NADP+
-
?
2.1.2.11 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O
-
Corynebacterium glutamicum tetrahydrofolate + 2-dehydropantoate
-
?
2.1.2.11 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O
-
Corynebacterium glutamicum ATCC 13032 tetrahydrofolate + 2-dehydropantoate
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.169 PanE
-
Escherichia coli
2.1.2.11 PanB
-
Corynebacterium glutamicum

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.169 NADPH
-
Escherichia coli

General Information

EC Number General Information Comment Organism
2.1.2.11 metabolism the enzyme is involved in D-pantothenic acid biosynthesis Corynebacterium glutamicum