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Literature summary extracted from

  • Fedosejevs, E.T.; Feil, R.; Lunn, J.E.; Plaxton, W.C.
    The signal metabolite trehalose-6-phosphate inhibits the sucrolytic activity of sucrose synthase from developing castor beans (2018), FEBS Lett., 592, 2525-2532 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.13 D-glucose 6-phosphate 1 mM D-glucose 6-phosphate slightly decreases the enzyme activity by less than 20% Ricinus communis
2.4.1.13 additional information 1 mM D-glucose 1-phosphate has no effect on the enzyme Ricinus communis
2.4.1.13 trehalose 6-phosphate more than 90% inhibition at 1 mM Ricinus communis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.13 0.032
-
 sucrose in the presence of 0.2 mM trehalose 6-phosphate, at pH 7.0 and 25°C Ricinus communis
2.4.1.13 0.037
-
 sucrose in the absence of trehalose 6-phosphate, at pH 7.0 and 25°C Ricinus communis
2.4.1.13 0.052
-
 UDP in the presence of 0.2 mM trehalose 6-phosphate, at pH 7.0 and 25°C Ricinus communis
2.4.1.13 0.061
-
 UDP in the absence of trehalose 6-phosphate, at pH 7.0 and 25°C Ricinus communis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.13 Mg2+ 1 mM used in assay conditions Ricinus communis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.13 NDP-alpha-D-glucose + D-fructose Ricinus communis
-
 NDP + sucrose
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.13 Ricinus communis
-
 cultivar Baker 296
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.13 phosphoprotein phosphorylated at Ser11 by the Ca2+-dependent protein kinase CDPK2 Ricinus communis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.13 seed
-
 Ricinus communis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.13 NDP-alpha-D-glucose + D-fructose
-
 Ricinus communis NDP + sucrose
-
 r
2.4.1.13 UDP + sucrose
-
 Ricinus communis UDP-alpha-D-glucose + D-fructose
-
 r

Subunits

EC Number Subunits Comment Organism
2.4.1.13 homotetramer 4 * 93000, SDS-PAGE Ricinus communis

Synonyms

EC Number Synonyms Comment Organism
2.4.1.13 SUS1
-
 Ricinus communis

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.4.1.13 0.201
-
 at pH 7.0 and 25°C Ricinus communis trehalose 6-phosphate