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Literature summary extracted from

  • Stewart, E.; Katzen, F.; Beckwith, J.
    Six conserved cysteines of the membrane protein DsbD are required for the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli (1999), EMBO J., 18, 5963-5971 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.8.4.16 C122A active site mutant Escherichia coli
1.8.4.16 C128A active site mutant Escherichia coli
1.8.4.16 C13A the mutant shows wild type activity Escherichia coli
1.8.4.16 C182A active site mutant Escherichia coli
1.8.4.16 C301A the mutant shows wild type activity Escherichia coli
1.8.4.16 C304A active site mutant Escherichia coli
1.8.4.16 C480A/C483A active site mutant Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.4.16 cytoplasmic membrane
-
 Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.4.16 a [protein] with reduced L-cysteine residues + thioredoxin disulfide Escherichia coli overall reaction a [protein] carrying a disulfide bond + thioredoxin
-
 ?
1.8.4.16 [DsbC protein] carrying a disulfide bond + thioredoxin Escherichia coli
-
 [DsbC protein] with reduced L-cysteine residues + thioredoxin disulfide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.16 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.16 a [protein] with reduced L-cysteine residues + thioredoxin disulfide overall reaction Escherichia coli a [protein] carrying a disulfide bond + thioredoxin
-
 ?
1.8.4.16 [DsbC protein] carrying a disulfide bond + thioredoxin
-
 Escherichia coli [DsbC protein] with reduced L-cysteine residues + thioredoxin disulfide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.16 DsbD
-
 Escherichia coli