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Literature summary extracted from
- Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub (2019), eLife, 8, e44040 .
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.3.1.108 | synapse | - |
Caenorhabditis elegans | 45202 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.3.1.108 | Caenorhabditis elegans | Q23192 | - |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.3.1.108 | ATAT-2 | - |
Caenorhabditis elegans |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 2.3.1.108 | physiological function | alpha-tubulin acetyltransferase ATAT-2 and the signaling hub RPM-1 are required presynaptically to maintain stable synapses. The acetyltransferase activity of ATAT-2 is required for synapse maintenance. RPM-1 is a hub in a genetic network composed of ATAT-2, PTRN-1 and DLK-1. ATAT-2 functions independent of the DLK-1 MAPK and likely acts downstream of RPM-1 | Caenorhabditis elegans |
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