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Literature summary extracted from

  • Tonin, A.; Da Silva, A.; Zanini, D.; Pelinson, L.; Schetinger, M.; Camillo, G.; Vogel, F.; de La Rue, M.; Jaques, J.; Lopes, S.
    Biochemical detection of enzymes NTPDase in tachyzoites of Toxoplasma gondii and possible functional correlations (2015), Comp. Clin. Pathol., 24, 393-397 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.5 azide inhibition of NTPDase activity of the Toxoplasma gondii is directly proportional to the largest concentration of azide used to ATP and ADP substratum Toxoplasma gondii

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.5 Ca2+ required Toxoplasma gondii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.5 ADP + H2O Toxoplasma gondii
-
 AMP + phosphate
-
 ?
3.6.1.5 ADP + H2O Toxoplasma gondii RH
-
 AMP + phosphate
-
 ?
3.6.1.5 ATP + H2O Toxoplasma gondii
-
 ADP + phosphate
-
 ?
3.6.1.5 ATP + H2O Toxoplasma gondii RH
-
 ADP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.5 Toxoplasma gondii
-
 propagated in BALB/c mice
-
3.6.1.5 Toxoplasma gondii RH
-
 propagated in BALB/c mice
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.5 tachyzoite
-
 Toxoplasma gondii
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.5 ADP + H2O
-
 Toxoplasma gondii AMP + phosphate
-
 ?
3.6.1.5 ADP + H2O
-
 Toxoplasma gondii RH AMP + phosphate
-
 ?
3.6.1.5 ATP + H2O
-
 Toxoplasma gondii ADP + phosphate
-
 ?
3.6.1.5 ATP + H2O
-
 Toxoplasma gondii RH ADP + phosphate
-
 ?
3.6.1.5 additional information the activity of NTPDase for substrate ATP is superior to ADP. For the hydrolysis of ATP, a decreasing curve is observed, since increased concentration of substrate consequently reduces NTPDase activity. The opposite occurs with the hydrolysis of ADP, since increases in NTPDase activity are directly proportional to the elevation of substrate in the reaction Toxoplasma gondii ?
-
-
3.6.1.5 additional information the activity of NTPDase for substrate ATP is superior to ADP. For the hydrolysis of ATP, a decreasing curve is observed, since increased concentration of substrate consequently reduces NTPDase activity. The opposite occurs with the hydrolysis of ADP, since increases in NTPDase activity are directly proportional to the elevation of substrate in the reaction Toxoplasma gondii RH ?
-
-

Synonyms

EC Number Synonyms Comment Organism
3.6.1.5 NTPDase
-
 Toxoplasma gondii

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.1.5 37
-
-
 Toxoplasma gondii

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.5 8
-
-
 Toxoplasma gondii