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Literature summary extracted from

  • Luo, Y.; Wu, Y.; Munyampundu, J.
    Role of alkyl hydroperoxide reductase subunit C (AhpC) as a peroxiredoxin in Leptospira interrogans against oxidative stress (2018), Chin. J. Microbiol. Immunol., 38, 193-198 .
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.1.24 successfully expressed in a prokaryotic expression system Leptospira interrogans

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.24 Leptospira interrogans
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-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.11.1.24
-
Leptospira interrogans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.24 thioredoxin + H2O2 the ability of AhpC in reducing hydrogen peroxide is depend on the thioredoxin/thioredoxin reductase system. Cys47 (a peroxidatic cysteine) and Cys167 (a resolving cysteine) were critical to maintaining the enzymatic activity of AhpC Leptospira interrogans thioredoxin disulfide + 2 H2O
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Synonyms

EC Number Synonyms Comment Organism
1.11.1.24 AhpC
-
Leptospira interrogans
1.11.1.24 alkyl hydroperoxide reductase subunit C
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Leptospira interrogans

General Information

EC Number General Information Comment Organism
1.11.1.24 physiological function AhpC of Leptospira interrogans is a thioredoxin-dependent peroxiredoxin that plays an important role in protecting Leptospira interrogans against oxidative stress in macrophages Leptospira interrogans