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Literature summary extracted from

  • Seelhorst, K.; Pahnke, K.; Meier, C.; Hahn, U.
    Tagging glycoproteins with fluorescently labeled GDP-fucoses by Using alpha1,3-fucosyltransferases (2015), ChemBioChem, 16, 1919-1924 .
    View publication on PubMed

Application

EC Number Application Comment Organism
2.4.1.152 analysis synthesis of fluorescein-isothiocyanate-labeled and carboxyfluorescein-labeled NDP-beta-L-fucose derivatives, and application in labeling of different glycoproteins with the aid of fucosyltransferases. The fluorescein-isothiocyanate-labeled fucose is the best of these substrates, and the bacterial enzyme FucT tolerates the fluorescent substrates better than human fucosyltransferases Homo sapiens
2.4.1.152 analysis synthesis of fluorescein-isothiocyanate-labeled and carboxyfluorescein-labeled NDP-beta-L-fucose derivatives, and application in labeling of different glycoproteins with the aid of fucosyltransferases. The fluorescein-isothiocyanate-labeled fucose is the best of these substrates, and the bacterial enzyme FucT tolerates the fluorescent substrates better than human fucosyltransferases Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.152 Helicobacter pylori O30511
-
-
2.4.1.152 Homo sapiens Q11130
-
-
2.4.1.152 Homo sapiens Q9Y231
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.152 GDP-alpha-L-fucose + asialofetuin
-
Homo sapiens GDP + ?
-
?
2.4.1.152 GDP-alpha-L-fucose + asialofetuin
-
Helicobacter pylori GDP + ?
-
?
2.4.1.152 GDP-alpha-L-fucose + fetuin
-
Homo sapiens GDP + ?
-
?
2.4.1.152 GDP-alpha-L-fucose + fetuin
-
Helicobacter pylori GDP + ?
-
?
2.4.1.152 GDP-alpha-L-fucose + glycoprotein gp130
-
Homo sapiens GDP + ?
-
?
2.4.1.152 GDP-alpha-L-fucose + glycoprotein gp130
-
Helicobacter pylori GDP + ?
-
?
2.4.1.152 additional information enzyme accepts fluorescein-isothiocyanate-labeled fucose and carboxyfluorescein-labeled fucose. Fluorescein-isothiocyanate-labeled NDP-beta-L-fucose is the best of these substrates Homo sapiens ?
-
-
2.4.1.152 additional information enzyme accepts fluorescein-isothiocyanate-labeled fucose and carboxyfluorescein-labeled fucose. Fluorescein-isothiocyanate-labeled NDP-beta-L-fucose is the best of these substrates Helicobacter pylori ?
-
-

Synonyms

EC Number Synonyms Comment Organism
2.4.1.152 FucT
-
Helicobacter pylori
2.4.1.152 FUT7
-
Homo sapiens
2.4.1.152 Fut9
-
Homo sapiens