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Literature summary extracted from

  • Evangelisti, E.; Yunusov, T.; Shenhav, L.; Schornack, S.
    N-acetyltransferase AAC(3)-I confers gentamicin resistance to Phytophthora palmivora and Phytophthora infestans (2019), BMC Microbiol., 19, 265 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.60 expressed in Phytophthora palmivora strain LILI and Phytophthora infestans strain 88069 Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.60 acetyl-CoA + astromicin Pseudomonas aeruginosa
-
 CoA + N3-acetylastromicin
-
 ?
2.3.1.60 acetyl-CoA + gentamicin Pseudomonas aeruginosa
-
 CoA + N3-acetylgentamicin
-
 ?
2.3.1.60 acetyl-CoA + sisomicin Pseudomonas aeruginosa
-
 CoA + N3-acetylsisomicin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.60 Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.60 acetyl-CoA + astromicin
-
 Pseudomonas aeruginosa CoA + N3-acetylastromicin
-
 ?
2.3.1.60 acetyl-CoA + gentamicin
-
 Pseudomonas aeruginosa CoA + N3-acetylgentamicin
-
 ?
2.3.1.60 acetyl-CoA + sisomicin
-
 Pseudomonas aeruginosa CoA + N3-acetylsisomicin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.60 AAC(3)-I
-
 Pseudomonas aeruginosa
2.3.1.60 aacC1
-
 Pseudomonas aeruginosa
2.3.1.60 aminoglycoside 3-Nacetyltransferase I
-
 Pseudomonas aeruginosa

General Information

EC Number General Information Comment Organism
2.3.1.60 physiological function the enzyme confers gentamicin resistance but retains geneticin susceptibility Pseudomonas aeruginosa