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Literature summary extracted from

  • Weiss, A.K.H.; Loeffler, J.R.; Liedl, K.R.; Gstach, H.; Jansen-Duerr, P.
    The fumarylacetoacetate hydrolase (FAH) superfamily of enzymes multifunctional enzymes from microbes to mitochondria (2018), Biochem. Soc. Trans., 46, 295-309 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.7.1.2 cytosol
-
 Homo sapiens 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.7.1.2 Acinetobacter baumannii A0A0D5YDA5
-
-
3.7.1.2 Cupriavidus gilardii A0A0M3SVN7
-
-
3.7.1.2 Cupriavidus gilardii CR3 A0A0M3SVN7
-
-
3.7.1.2 Homo sapiens P16930
-
-
3.7.1.2 Phaeobacter gallaeciensis A0A1B0ZSC0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.7.1.2 4-fumarylacetoacetate + H2O
-
 Acinetobacter baumannii acetoacetate + fumarate
-
 ?
3.7.1.2 4-fumarylacetoacetate + H2O
-
 Homo sapiens acetoacetate + fumarate
-
 ?
3.7.1.2 4-fumarylacetoacetate + H2O
-
 Phaeobacter gallaeciensis acetoacetate + fumarate
-
 ?
3.7.1.2 4-fumarylacetoacetate + H2O
-
 Cupriavidus gilardii acetoacetate + fumarate
-
 ?
3.7.1.2 4-fumarylacetoacetate + H2O
-
 Cupriavidus gilardii CR3 acetoacetate + fumarate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.7.1.2 FAH
-
 Homo sapiens
3.7.1.2 NagK
-
 Acinetobacter baumannii
3.7.1.2 NagK
-
 Phaeobacter gallaeciensis
3.7.1.2 NagK
-
 Cupriavidus gilardii