EC Number | Application | Comment | Organism |
---|---|---|---|
2.4.1.5 | medicine | the effects of sodium ions on dextran succrase activity are specific, thus it can be useful to block its catalytic activity, and reducing the cariogenic potential of Streptococcus mutans | Streptococcus mutans |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.5 | NaCl | only the hydrolytic activity of the dextransuccrase is influenced by sodium ions, whereas there is no effect on glucosyltransferase activity. 0.5 mM, 65% inhibition of hydrolytic activity, 20 mM, 90% inhibition of hydrolytic activity. The enzyme shows biphasic effects in response to Na+ ions. The enzyme activity is restored by 86% after dialysis compared to the control enzyme preparation. No effect on in presence of other monovalent cations (Rb+, Cs+, and K+). The effects of sodium ions on dextransuccrase activity are specific, thus it can be useful to block its catalytic activity, and reducing the cariogenic potential of Streptococcus mutans | Streptococcus mutans |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.1.5 | 21.36 | - |
sucrose | pH 6.8, 37°C | Streptococcus mutans | |
2.4.1.5 | 71.92 | - |
sucrose | pH 5.2, 37°C | Streptococcus mutans | |
2.4.1.5 | 285.22 | - |
sucrose | pH 8.0, 37°C | Streptococcus mutans |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.5 | Streptococcus mutans | - |
- |
- |
2.4.1.5 | Streptococcus mutans MTCC 890 | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.5 | sucrose + dextran | dextransucrase exhibits both hydrolytic and transferase activities. It catalyses the transfer of glucosyl residues from sucrose to dextran to form complex polysaccharides | Streptococcus mutans | ? | - |
? | |
2.4.1.5 | sucrose + dextran | dextransucrase exhibits both hydrolytic and transferase activities. It catalyses the transfer of glucosyl residues from sucrose to dextran to form complex polysaccharides | Streptococcus mutans MTCC 890 | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.1.5 | 37 | - |
- |
Streptococcus mutans |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.1.5 | 6.8 | - |
- |
Streptococcus mutans |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.4.1.5 | metabolism | key enzyme in Streptococcus mutans for the metabolism of sucrose which helps in the adherence and accumulation of bacteria on tooth surface leading to the formation of dental caries | Streptococcus mutans |