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Literature summary extracted from

  • Deng, X.; Sun, H.; Gao, X.; Gong, H.; Lu, W.; Chu, Y.; Zhou, L.; Ye., D.
    Development, validation, and application of a novel method for mammalian sphingomyelin synthase activity measurement (2012), Anal. Lett., 45, 1581-1589 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.8.27 D609 i.e. potassium tricyclo[5.2.1.0(2,6)]-decan-8-yl dithiocarbonate Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.8.27 0.00749
-
 6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)-sphingosine at pH 7.4 and 37°C Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.8.27 Mn2+ 3 mM used in assay conditions Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.27 6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)-sphingosine + 1,2-dimyristoyl-sn-glycero-3-phosphocholine Mus musculus
-
 N-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-epsilon-aminohexanoyl)sphingosylphosphorylcholine + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.27 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.27 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.27 6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)-sphingosine + 1,2-dimyristoyl-sn-glycero-3-phosphocholine
-
 Mus musculus N-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-epsilon-aminohexanoyl)sphingosylphosphorylcholine + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.8.27 SMS
-
 Mus musculus