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Literature summary extracted from

  • Clark, C.C.; Mebius, M.M.; de Maat, S.; Tielens, A.G.M.; de Groot, P.G.; Urbanus, R.T.; Fijnheer, R.; Hazenberg, B.P.C.; van Hellemond, J.J.; Maas, C.
    Truncation of ADAMTS13 by plasmin enhances its activity in plasma (2018), Thromb. Haemost., 118, 471-479 .
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.87 plasmin truncation of the enzyme by plasmin enhances its activity in blood plasma Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.87 additional information Homo sapiens plasmin cleaves and ultimately inactivates the enzyme ?
-
?
3.4.24.87 von Willebrand factor + H2O Homo sapiens
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.87 Homo sapiens Q76LX8
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.87 blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.87 FRETS-von Willebrand factor 73 + H2O
-
Homo sapiens ?
-
?
3.4.24.87 additional information plasmin cleaves and ultimately inactivates the enzyme Homo sapiens ?
-
?
3.4.24.87 von Willebrand factor + H2O
-
Homo sapiens ?
-
?

Subunits

EC Number Subunits Comment Organism
3.4.24.87 ? x * 190000, full-length enzyme, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.4.24.87 a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13
-
Homo sapiens
3.4.24.87 ADAMTS13
-
Homo sapiens