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Literature summary extracted from

  • Saenz-Mendez, P.; Katz, A.; Perez-Kempner, M.L.; Ventura, O.N.; Vazquez, M.
    Structural insights into human microsomal epoxide hydrolase by combined homology modeling, molecular dynamics simulations, and molecular docking calculations (2017), Proteins, 85, 720-730 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.9 valpromide
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Homo sapiens P07099
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.3.2.9 cis-stilbene oxide + H2O = (1R,2R)-1,2-diphenylethane-1,2-diol ring-opening reaction mechanism, overview Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 styrene oxide + H2O
-
Homo sapiens 1-phenylethane-1,2-diol
-
?

Synonyms

EC Number Synonyms Comment Organism
3.3.2.9 EPHX1
-
Homo sapiens
3.3.2.9 mEH
-
Homo sapiens
3.3.2.9 Microsomal epoxide hydrolase
-
Homo sapiens

General Information

EC Number General Information Comment Organism
3.3.2.9 additional information homology structure modeling of human microsomal epoxide hydrolase using multiple templates, catalytic triad consits of Asp-His-Glu, and role of the oxyanion hole and the conserved motif (HGXP) in epoxide hydrolases, overview. Proposed mechanism for the ring-opening reaction catalyzed by mEH, analysis of substrate-enzyme interactions, docking and molecular dynamic simulation Homo sapiens