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Literature summary extracted from

  • Jansen, R.S.; Addie, R.; Merkx, R.; Fish, A.; Mahakena, S.; Bleijerveld, O.B.; Altelaar, M.; IJlst, L.; Wanders, R.J.; Borst, P.; van de Wetering, K.
    N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids (2015), Proc. Natl. Acad. Sci. USA, 112, 6601-6606 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.18 Homo sapiens Q96KP4
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.13.18 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.18 lactate + L-isoleucine
-
 Homo sapiens N-L-lactoyl-L-isoleucine + H2O
-
 ?
3.4.13.18 lactate + L-phenylalanine
-
 Homo sapiens N-L-lactoyl-L-phenylalanine + H2O
-
 ?
3.4.13.18 lactate + L-tryptophan
-
 Homo sapiens N-L-lactoyl-L-tryptophan + H2O
-
 ?
3.4.13.18 lactate + L-tyrosine
-
 Homo sapiens N-L-lactoyl-L-tyrosine + H2O
-
 ?
3.4.13.18 additional information CNDP2 catalyzes the formation of N-lactoyl-amino acids. The plasma levels of of N-lactoyl-amino acids strongly correlate with plasma levels of lactate and amino acids Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.13.18 CNDP2
-
 Homo sapiens