EC Number | Application | Comment | Organism |
---|---|---|---|
4.2.1.175 | medicine | in mice colonized by a wild-type Clostridium sporogenes strain, the mean indolepropionic acid concentration is around 80 microM, but in mice colonized with theFfldC mutant, indolepropionic acid is undetectable. Animals colonized by the FldC mutant exhibit significantly elevated frequencies of circulating myeloid cells, including neutrophils and classical (Ly6C+) monocytes, as well as increased antigen-experienced effector/memory T cells. Mice colonized by the FldC mutant strain show a significant increase in circulating Clostridium sporogenes-specific IgG | Clostridium sporogenes |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.8.15 | 3-(1H-indol-3-yl)propanoate + electron-transfer flavoprotein EtfA-EtfB | Clostridium sporogenes | - |
3-(indol-3-yl)acrylate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | 3-(1H-indol-3-yl)propanoate + electron-transfer flavoprotein EtfA-EtfB | Clostridium sporogenes ATCC 15579 | - |
3-(indol-3-yl)acrylate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | 3-phenylpropanoate + electron-transfer flavoprotein EtfA-EtfB | Clostridium sporogenes | - |
trans-cinnamate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | 3-phenylpropanoate + electron-transfer flavoprotein EtfA-EtfB | Clostridium sporogenes ATCC 15579 | - |
trans-cinnamate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | phloretate + electron-transfer flavoprotein EtfA-EtfB | Clostridium sporogenes | - |
4-coumarate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | phloretate + electron-transfer flavoprotein EtfA-EtfB | Clostridium sporogenes ATCC 15579 | - |
4-coumarate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.8.15 | Clostridium sporogenes | J7TF92 | - |
- |
1.3.8.15 | Clostridium sporogenes ATCC 15579 | J7TF92 | - |
- |
4.2.1.175 | Clostridium sporogenes | Q93AL9 and Q93AL8 | Q93AL9 i.e. alpha-subunit FldB, Q93AL8 i.e. beta-subunit FldC | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.8.15 | 3-(1H-indol-3-yl)propanoate + electron-transfer flavoprotein EtfA-EtfB | - |
Clostridium sporogenes | 3-(indol-3-yl)acrylate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | 3-(1H-indol-3-yl)propanoate + electron-transfer flavoprotein EtfA-EtfB | - |
Clostridium sporogenes ATCC 15579 | 3-(indol-3-yl)acrylate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | 3-phenylpropanoate + electron-transfer flavoprotein EtfA-EtfB | - |
Clostridium sporogenes | trans-cinnamate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | 3-phenylpropanoate + electron-transfer flavoprotein EtfA-EtfB | - |
Clostridium sporogenes ATCC 15579 | trans-cinnamate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | phloretate + electron-transfer flavoprotein EtfA-EtfB | - |
Clostridium sporogenes | 4-coumarate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? | |
1.3.8.15 | phloretate + electron-transfer flavoprotein EtfA-EtfB | - |
Clostridium sporogenes ATCC 15579 | 4-coumarate + reduced electron-transfer flavoprotein EtfA-EtfB | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.8.15 | acdA | - |
Clostridium sporogenes |
1.3.8.15 | acyl-CoA dehydrogenase | - |
Clostridium sporogenes |
4.2.1.175 | FldC | - |
Clostridium sporogenes |
EC Number | General Information | Comment | Organism |
---|---|---|---|
4.2.1.175 | physiological function | FldC is essential for the reductive metabolism of aromatic amino acids phenylalanine, tyrosine and tryptophan | Clostridium sporogenes |