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Literature summary extracted from
- Evaluation of flavonols and derivatives as human cathepsin B inhibitor (2015), Nat. Prod. Res., 29, 2212-2214 .
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.22.1 | medicine | the enzyme is involved in tumour progression and represents a potential therapeutic target in cancer | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.1 | myricetin | - |
Homo sapiens |  |
| 3.4.22.1 | quercetin | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.1 | Homo sapiens | P07858 | - |
- |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 3.4.22.1 | 0.0049 | - |
pH and temperature not specified in the publication | Homo sapiens | myricetin | |
| 3.4.22.1 | 0.0082 | - |
pH and temperature not specified in the publication | Homo sapiens | quercetin | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.22.1 | physiological function | involved in tumour progression | Homo sapiens |
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Release 2023.1 (January 2023)
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