EC Number | General Stability | Organism |
---|---|---|
3.4.24.87 | no enzyme activity decrease is seen in heparinized plasma, but the addition of citrate causes enzyme instability at 37°C | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.87 | Ca2+ | the catalytic domain of the enzyme possesses up to three putative Ca2+ binding sites | Homo sapiens | |
3.4.24.87 | Zn2+ | the catalytic domain of the enzyme possesses one Zn2+ binding site. Zn2+ is required to stabilize enzyme structure at physiologic temperature | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.87 | von Willebrand factor + H2O | Homo sapiens | - |
? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.87 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.24.87 | blood plasma | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.87 | FRETS-von Willebrand factor 73 + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.24.87 | von Willebrand factor + H2O | - |
Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.87 | ADAMTS13 | - |
Homo sapiens |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.24.87 | 25 | 37 | the enzyme is stable at room temperature for up to 24 h irrespective of the presence of citrate (0.38% (w/v)). However, at 37°C, citrate causes a time-dependent activity decrease | Homo sapiens |