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Literature summary extracted from
- Separase Function beyond cohesion cleavage and an emerging oncogene (2017), J. Cell. Biochem., 118, 1283-1299 .
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.49 | Arabidopsis thaliana | A0A1P8B3N4 | - |
- |
| 3.4.22.49 | Caenorhabditis elegans | - |
- |
- |
| 3.4.22.49 | Drosophila melanogaster | Q9VRN6 | - |
- |
| 3.4.22.49 | Picea abies | R4XPW1 | - |
- |
| 3.4.22.49 | Saccharomyces cerevisiae | Q03018 | - |
- |
| 3.4.22.49 | Schizosaccharomyces pombe | P18296 | - |
- |
| 3.4.22.49 | Schizosaccharomyces pombe ATCC 24843 | P18296 | - |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.22.49 | AtESP | - |
Arabidopsis thaliana |
| 3.4.22.49 | Cut1 | - |
Schizosaccharomyces pombe |
| 3.4.22.49 | Esp1 | - |
Saccharomyces cerevisiae |
| 3.4.22.49 | sep-1 | - |
Caenorhabditis elegans |
| 3.4.22.49 | SSE | - |
Drosophila melanogaster |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.22.49 | physiological function | chiasmata resolution and segregation of homologous chromosome pair. Role in DNA repair. Assembly and elongation of spindle at mitotic anaphase. Spindle formation in meiosis. Karyokinesis (division of nucleus). Spindle midzone assembly. Apoptosis promotion. Cleavage of Slk19. Cdc14 activation and release of Cdc14 from nucleolus | Saccharomyces cerevisiae |
| 3.4.22.49 | physiological function | involved in proper positioning of the centrosomes during the first asymmetric mitotic division, in the development of egg shell and in membrane trafficking | Caenorhabditis elegans |
| 3.4.22.49 | physiological function | role in DNA repair. Involved in positioning of spindle pole body | Schizosaccharomyces pombe |
| 3.4.22.49 | physiological function | the enzyme is involved in cell expansion | Picea abies |
| 3.4.22.49 | physiological function | the enzyme is involved in establishment of cell polarity and cytokinesis, in microtubule polymerization and Kin7 activation | Arabidopsis thaliana |
| 3.4.22.49 | physiological function | the enzyme is involved in reorganization and dynamics in epithelial cells, in telomere capping and in inactivation of alternative conjunction at anaphase I onset | Drosophila melanogaster |
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