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Literature summary extracted from

  • Ouyang, W.; Guo, P.; Fang, H.; Frucht, D.M.
    Anthrax lethal toxin rapidly reduces c-Jun levels by inhibiting c-Jun gene transcription and promoting c-Jun protein degradation (2017), J. Biol. Chem., 292, 17919-17927 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.83 Bacillus anthracis P15917
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.83 mitogen-activated protein kinase kinase 1 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 mitogen-activated protein kinase kinase 2 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 mitogen-activated protein kinase kinase 3 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 mitogen-activated protein kinase kinase 4 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 mitogen-activated protein kinase kinase 6 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 additional information the enzyme does not degrade mitogen-activated protein kinase kinase 7, Erk1/2, p38 and JNK1/2 Bacillus anthracis ?
-
 ?
3.4.24.83 phosphorylated ERK1/2 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 phosphorylated JNK1/2 + H2O
-
 Bacillus anthracis ?
-
 ?
3.4.24.83 phosphorylated p38 + H2O
-
 Bacillus anthracis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.83 anthrax lethal toxin
-
 Bacillus anthracis

General Information

EC Number General Information Comment Organism
3.4.24.83 physiological function the enzyme rapidly reduces c-Jun levels by inhibiting c-Jun gene transcription and promoting c-Jun protein degradation Bacillus anthracis