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Literature summary extracted from

  • Hosomi, A.; Tanabe, K.; Hirayama, H.; Kim, I.; Rao, H.; Suzuki, T.
    Identification of an Htm1 (EDEM)-dependent, Mns1-independent endoplasmic reticulum-associated degradation (ERAD) pathway in Saccharomyces cerevisiae Application of a novel assay for glycoprotein ERAD (2010), J. Biol. Chem., 285, 24324-24334 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.2.1.210 E222Q inactive Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.210 endoplasmic reticulum
-
 Saccharomyces cerevisiae 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + H2O Saccharomyces cerevisiae
-
 Man7GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + H2O Saccharomyces cerevisiae BY4741
-
 Man7GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y] + H2O Saccharomyces cerevisiae
-
 Man7GlcNAc2-[carboxypeptidase Y] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y] + H2O Saccharomyces cerevisiae BY4741
-
 Man7GlcNAc2-[carboxypeptidase Y] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain-transmembrane-Leu2] (isomer 8A1,2,3B1,3) + H2O Saccharomyces cerevisiae
-
 Man7GlcNAc2-[ricin A-chain-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain-transmembrane-Leu2] (isomer 8A1,2,3B1,3) + H2O Saccharomyces cerevisiae BY4741
-
 Man7GlcNAc2-[ricin A-chain-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain] (isomer 8A1,2,3B1,3) + H2O Saccharomyces cerevisiae
-
 Man7GlcNAc2-[ricin A-chain] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain] (isomer 8A1,2,3B1,3) + H2O Saccharomyces cerevisiae BY4741
-
 Man7GlcNAc2-[ricin A-chain] + D-mannopyranose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.210 Saccharomyces cerevisiae
-
-
-
3.2.1.210 Saccharomyces cerevisiae BY4741
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + H2O
-
 Saccharomyces cerevisiae Man7GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + H2O
-
 Saccharomyces cerevisiae BY4741 Man7GlcNAc2-[carboxypeptidase Y-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y] + H2O
-
 Saccharomyces cerevisiae Man7GlcNAc2-[carboxypeptidase Y] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[carboxypeptidase Y] + H2O
-
 Saccharomyces cerevisiae BY4741 Man7GlcNAc2-[carboxypeptidase Y] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain-transmembrane-Leu2] (isomer 8A1,2,3B1,3) + H2O
-
 Saccharomyces cerevisiae Man7GlcNAc2-[ricin A-chain-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain-transmembrane-Leu2] (isomer 8A1,2,3B1,3) + H2O
-
 Saccharomyces cerevisiae BY4741 Man7GlcNAc2-[ricin A-chain-transmembrane-Leu2] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain] (isomer 8A1,2,3B1,3) + H2O
-
 Saccharomyces cerevisiae Man7GlcNAc2-[ricin A-chain] + D-mannopyranose
-
 ?
3.2.1.210 Man8GlcNAc2-[ricin A-chain] (isomer 8A1,2,3B1,3) + H2O
-
 Saccharomyces cerevisiae BY4741 Man7GlcNAc2-[ricin A-chain] + D-mannopyranose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.210 EDEM
-
 Saccharomyces cerevisiae
3.2.1.210 ERAD-related alpha-mannosidase
-
 Saccharomyces cerevisiae
3.2.1.210 Htm1
-
 Saccharomyces cerevisiae