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Literature summary extracted from
- Site-1 protease is required for the generation of soluble (pro)renin receptor (2017), J. Biochem., 161, 369-379 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.112 | PF429242 | inhibotor suppresses the formation of soluble (pro)renin receptor | Cricetulus griseus |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.112 | Cricetulus griseus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.112 | (pro)renin receptor + H2O | - |
Cricetulus griseus | soluble (pro)renin receptor + ? | - |
? | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.21.112 | physiological function | siRNA-mediated reduction of endogenous S1P in cChinese hamster ovary cells attenuates soluble (pro)renin receptor generation. Overexpression of S1P by transient transfection in this cell line increases s(P)RR generation. The S1P inhibitor PF429242 suppresses the generation of soluble (pro)renin receptor | Cricetulus griseus |
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Release 2023.1 (January 2023)
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