Literature summary extracted from

Hirakawa, H.; Schaefer, A.L.; Greenberg, E.P.; Harwood, C.S.
Anaerobic p-coumarate degradation by Rhodopseudomonas palustris and identification of CouR, a MarR repressor protein that binds p-coumaroyl coenzyme A (2012), J. Bacteriol., 194, 1960-1967 .

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.1.2.61	feruloyl-CoA + H2O	Rhodopseudomonas palustris	the enzyme is required for p-coumarate degradation	vanillin + acetyl-CoA	-	?
4.1.2.61	feruloyl-CoA + H2O	Rhodopseudomonas palustris ATCC BAA-98	the enzyme is required for p-coumarate degradation	vanillin + acetyl-CoA	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.2.61	Rhodopseudomonas palustris	Q6N8W7	-	-
4.1.2.61	Rhodopseudomonas palustris ATCC BAA-98	Q6N8W7	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.2.61	feruloyl-CoA + H2O	-	Rhodopseudomonas palustris	vanillin + acetyl-CoA	-	?
4.1.2.61	feruloyl-CoA + H2O	the enzyme is required for p-coumarate degradation	Rhodopseudomonas palustris	vanillin + acetyl-CoA	-	?
4.1.2.61	feruloyl-CoA + H2O	-	Rhodopseudomonas palustris ATCC BAA-98	vanillin + acetyl-CoA	-	?
4.1.2.61	feruloyl-CoA + H2O	the enzyme is required for p-coumarate degradation	Rhodopseudomonas palustris ATCC BAA-98	vanillin + acetyl-CoA	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
4.1.2.61	NAD+	the enzyme binds an NAD+ cofactor	Rhodopseudomonas palustris

Expression

EC Number	Organism	Comment	Expression
4.1.2.61	Rhodopseudomonas palustris	Rpa1794 (CouR) represses couAB expression	down

General Information

EC Number	General Information	Comment	Organism
4.1.2.61	physiological function	the enzyme is required for p-coumarate degradation	Rhodopseudomonas palustris

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Release 2023.1 (January 2023)