Literature summary extracted from

Sattely, E.; Walsh, C.
A latent oxazoline electrophile for N-O-C bond formation in pseudomonine biosynthesis (2008), J. Am. Chem. Soc., 130, 12282-12284 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
6.2.1.61	expression in Escherichia coli	Pseudomonas entomophila
6.2.1.70	expression in Escherichia coli	Pseudomonas entomophila

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.2.1.61	Pseudomonas entomophila	Q1IAK8	-	-
6.2.1.61	Pseudomonas entomophila L48	Q1IAK8	-	-
6.2.1.70	Pseudomonas entomophila	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.2.1.70	ATP + L-threonine + holo-[L-threonyl-carrier protein]	-	Pseudomonas entomophila	AMP + diphosphate + L-threonyl-[L-threonyl-carrier protein]	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
6.2.1.61	pmsE	-	Pseudomonas entomophila
6.2.1.70	pmsD	-	Pseudomonas entomophila

General Information

EC Number	General Information	Comment	Organism
6.2.1.61	physiological function	enzyme is part of the pseudomonine non-ribosomal peptide synthetase complex	Pseudomonas entomophila
6.2.1.70	physiological function	in addition to the activation of L-Thr, PmsD is capable of promoting both amide coupling, and subsequent cyclodehydration	Pseudomonas entomophila

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Release 2023.1 (January 2023)