Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhang, W.W.; Wang, X.; Xie, P.; Yuan, S.T.; Liu, Q.H.
    Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism (2015), Int. J. Ophthalmol., 8, 453-458 .
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.83 Zn2+ zinc metalloproteinase Bacillus anthracis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.83 mitogen-activated protein kinase kinase 1 + H2O Bacillus anthracis
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.83 Bacillus anthracis P15917
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.83 mitogen-activated protein kinase kinase 1 + H2O
-
 Bacillus anthracis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.83 anthrax lethal toxin
-
 Bacillus anthracis
3.4.24.83 LeTx
-
 Bacillus anthracis

General Information

EC Number General Information Comment Organism
3.4.24.83 physiological function high glucose-induced activation of the MAPK extracellular signal-regulated kinase (ERK1/2) and p38 in the ARPE cell line is blocked by the enzyme. High glucose induced ARPE cells over proliferation is inhibited by the enzyme Bacillus anthracis