EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.355 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine9 | Mus musculus | overall reaction | 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 | - |
? | |
2.1.1.355 | S-adenosyl-L-methionine + a [histone H3]-L-lysine9 | Mus musculus | - |
S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9 | - |
? | |
2.1.1.355 | S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9 | Mus musculus | - |
S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 | - |
? | |
2.1.1.355 | S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine9 | Mus musculus | - |
S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine9 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.355 | Mus musculus | O54864 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.1.1.355 | C2C12 cell | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.355 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine9 | overall reaction | Mus musculus | 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 | - |
? | |
2.1.1.355 | S-adenosyl-L-methionine + a [histone H3]-L-lysine9 | - |
Mus musculus | S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9 | - |
? | |
2.1.1.355 | S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9 | - |
Mus musculus | S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 | - |
? | |
2.1.1.355 | S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine9 | - |
Mus musculus | S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine9 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.1.1.355 | ? | x * 43000, SDS-PAGE | Mus musculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.1.355 | H3-K9 methyltransferase | - |
Mus musculus |
2.1.1.355 | histone H3 methyltransferase | - |
Mus musculus |
2.1.1.355 | SUV39H1 | - |
Mus musculus |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.1.1.355 | Mus musculus | enzyme expression is decreased during myoblast differentiation | down |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.1.1.355 | malfunction | enzyme knockdown stimulates myoblast differentiation | Mus musculus |
2.1.1.355 | physiological function | the enzyme modulates myogenic gene expression and activation during skeletal muscle differentiation. The enzyme inhibits myoblast differentiation. The enzyme interacts with myocyte enhancer factor 2C directly and inhibits myocyte enhancer factor 2 transcription activity in a dose-dependent manner | Mus musculus |