Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Nishida, H.; Nishiyama, M.; Kobashi, N.; Kosuge, T.; Hoshino, T.; Yamane, H.
    A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway a key to the evolution of amino acid biosynthesis (1999), Genome Res., 9, 1175-1183 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.38 N-acetyl-L-glutamyl 5-phosphate + NADPH + H+ Thermus thermophilus
-
 N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate
-
 r
2.7.2.17 ATP + an [amino group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine Thermus thermophilus the enzyme participates in an L-lysine biosynthetric pathway ADP + phosphate + an [amino group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.38 Thermus thermophilus
-
-
-
2.7.2.17 Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.38 N-acetyl-L-glutamyl 5-phosphate + NADPH + H+
-
 Thermus thermophilus N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate
-
 r
2.7.2.17 ATP + an [amino group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine
-
 Thermus thermophilus ADP + phosphate + an [amino group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine
-
 ?
2.7.2.17 ATP + an [amino group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine the enzyme participates in an L-lysine biosynthetric pathway Thermus thermophilus ADP + phosphate + an [amino group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.38 lysY gene name, formerly named argC Thermus thermophilus
1.2.1.38 N-acetylglutamate 5-semialdehyde dehydrogenase
-
 Thermus thermophilus
2.7.2.17 argB
-
 Thermus thermophilus
2.7.2.17 lysZ
-
 Thermus thermophilus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.38 NADP+
-
 Thermus thermophilus

General Information

EC Number General Information Comment Organism
2.7.2.17 physiological function the enzyme participates in an L-lysine biosynthetric pathway Thermus thermophilus