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Literature summary extracted from

  • Sakaguchi, A.; Karachentsev, D.; Seth-Pasricha, M.; Druzhinina, M.; Steward, R.
    Functional characterization of the Drosophila Hmt4-20/Suv4-20 histone methyltransferase (2008), Genetics, 179, 317-322 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.361 S-adenosyl-L-methionine + a [histone H4]-N6,N6-dimethyl-L-lysine20 Drosophila melanogaster
-
 S-adenosyl-L-homocysteine + a [histone H4]-N6,N6,N6-trimethyl-L-lysine20
-
 ?
2.1.1.361 S-adenosyl-L-methionine + a [histone H4]-N6-methyl-L-lysine20 Drosophila melanogaster
-
 S-adenosyl-L-homocysteine + a [histone H4]-N6,N6-dimethyl-L-lysine20
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.361 Drosophila melanogaster Q9W5E0
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.361 larva
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.361 S-adenosyl-L-methionine + a [histone H4]-N6,N6-dimethyl-L-lysine20
-
 Drosophila melanogaster S-adenosyl-L-homocysteine + a [histone H4]-N6,N6,N6-trimethyl-L-lysine20
-
 ?
2.1.1.361 S-adenosyl-L-methionine + a [histone H4]-N6-methyl-L-lysine20
-
 Drosophila melanogaster S-adenosyl-L-homocysteine + a [histone H4]-N6,N6-dimethyl-L-lysine20
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.361 H4K20 di- and trimethyltransferase
-
 Drosophila melanogaster
2.1.1.361 histone H4 lysine20 trimethyltransferase
-
 Drosophila melanogaster
2.1.1.361 histone H4-K20 trimethyltransferase
-
 Drosophila melanogaster
2.1.1.361 Hmt4-20
-
 Drosophila melanogaster
2.1.1.361 Suv4-20
-
 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
2.1.1.361 physiological function the enzyme is not required for survival and does not control position-effect variegation Drosophila melanogaster