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Literature summary extracted from
- Molecular cloning and functional characterization of cathepsin B from the sea cucumber Apostichopus japonicus (2017), Fish Shellfish Immunol., 60, 447-457 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.22.1 | - |
Apostichopus japonicus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.22.1 | lysosome | - |
Apostichopus japonicus | 5764 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.22.1 | 36800 | - |
calculated from sequence | Apostichopus japonicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.1 | Apostichopus japonicus | A0A1S5RQP9 | - |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.22.1 | - |
Apostichopus japonicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.22.1 | intestine | high activity | Apostichopus japonicus | - |
| 3.4.22.1 | muscle | low activity | Apostichopus japonicus | - |
| 3.4.22.1 | respiratory system | intermediate activity | Apostichopus japonicus | - |
| 3.4.22.1 | tentacle | low activity | Apostichopus japonicus | - |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.22.1 | ? | x * 36000, SDS-PAGE | Apostichopus japonicus |
| 3.4.22.1 | ? | x * 36800, calculated from sequence | Apostichopus japonicus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.22.1 | CTSB | - |
Apostichopus japonicus |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 3.4.22.1 | Apostichopus japonicus | calculated from sequence | - |
5.8 |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 3.4.22.1 | Apostichopus japonicus | Vibrio splendidus challenged sea cucumber and LPS-exposed coelomocytes can both significantly boost the expression of cathepsin B | up |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.22.1 | malfunction | silencing of cathepsin B significantly depresses coelomocytes apoptosis rate by 0.16fold | Apostichopus japonicus |
| 3.4.22.1 | physiological function | the enzyme is an important immune factor | Apostichopus japonicus |
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Release 2023.1 (January 2023)
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