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Literature summary extracted from
- Antifungals targeted to sphingolipid synthesis Focus on inositol phosphorylceramide synthase (2000), Expert Opin. Investig. Drugs, 9, 1787-1796 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.3.1.298 | Alternaria toxin | - |
Saccharomyces cerevisiae | |
| 2.3.1.298 | australifungin | - |
Saccharomyces cerevisiae |  |
| 2.3.1.298 | fumonisin B1 | - |
Saccharomyces cerevisiae | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.3.1.298 | an ultra-long-chain fatty acyl-CoA + phytosphingosine | Saccharomyces cerevisiae | - |
phytoceramide + CoA | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.3.1.298 | Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.3.1.298 | an ultra-long-chain fatty acyl-CoA + phytosphingosine | - |
Saccharomyces cerevisiae | phytoceramide + CoA | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.3.1.298 | phytoceramide synthase | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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