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Literature summary extracted from

  • Kisliouk, T.; Yosefi, S.; Meiri, N.
    MiR-138 inhibits EZH2 methyltransferase expression and methylation of histone H3 at lysine 27, and affects thermotolerance acquisition (2011), Eur. J. Neurosci., 33, 224-235 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.356 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine27 Gallus gallus overall reaction 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
2.1.1.356 S-adenosyl-L-methionine + a [histone H3]-L-lysine27 Gallus gallus
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine27
-
 ?
2.1.1.356 S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine27 Gallus gallus
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
2.1.1.356 S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine27 Gallus gallus
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine27
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.356 Gallus gallus A0A1D5PN50
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.356 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine27 overall reaction Gallus gallus 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
2.1.1.356 S-adenosyl-L-methionine + a [histone H3]-L-lysine27
-
 Gallus gallus S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine27
-
 ?
2.1.1.356 S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine27
-
 Gallus gallus S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
2.1.1.356 S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine27
-
 Gallus gallus S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine27
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.356 EZH2 gene name, enhancer of zeste 2 Gallus gallus

Expression

EC Number Organism Comment Expression
2.1.1.356 Gallus gallus miR-138 injection inhibits enzyme expression after 6 h down