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Literature summary extracted from
- The M358R variant of alpha1-proteinase inhibitor inhibits coagulation factor VIIa (2016), Biochem. Biophys. Res. Commun., 470, 710-713 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.21 | alpha1-proteinase inhibitor variant M358R | - |
Homo sapiens | |
| 3.4.21.21 | antithrombin | requires heparin for maximal activity | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.21 | Factor X + H2O | Homo sapiens | - |
Factor Xa + ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.21 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.21 | Factor X + H2O | - |
Homo sapiens | Factor Xa + ? | - |
? | |
| 3.4.21.21 | S2288 + H2O | - |
Homo sapiens | D-Ile-Pro-Arg + 4-nitroaniline | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.21 | factor VIIa | - |
Homo sapiens |
| 3.4.21.21 | FVIIa | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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