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Literature summary extracted from

  • Wang, G.; Gao, Y.; Wang, H.; Wang, J.; Niu, X.
    Phloretin reduces cell injury and inflammation mediated by Staphylococcus aureus via targeting sortase B and the molecular mechanism (2018), Appl. Microbiol. Biotechnol., 102, 10665-10674 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.71 phloretin compound shows little anti-Staphylococcus aureus activity, but significantly inhibit SrtB activity in vitro. Phloretin reduces human alveolar epithelial cell damage caused by Staphylococcus aureus. Phloretin directly localizes in the active pocket of SrtB and blocks substrate binding Staphylococcus aureus

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.71 Staphylococcus aureus
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