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Literature summary extracted from

  • Couturier, J.
    Prosper, P.M.; Winger, A.M.; Hecker, A.; Hirasawa, M. Knaff, D.B.; Gans, P.; Jacquot, J.P.; Navaza, A.; Haouz, A.; Rouhier, N. In the absence of thioredoxins, what are the reductants for peroxiredoxins in Thermotoga maritima (2013), Antioxid. Redox Signal., 18, 1613-1622 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.1.25
-
 Thermotoga maritima

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.25 0.011
-
 glutaredoxin 2 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 0.0133
-
 H2O2 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 0.014
-
 glutaredoxin 2 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 0.018
-
 glutaredoxin 3 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 0.03
-
 glutaredoxin 3 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 0.0396
-
 H2O2 pH and temperature not specified in the publication Thermotoga maritima

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.11.1.25 17300
-
 calculated from sequence Thermotoga maritima
1.11.1.25 35000
-
 gel filtration Thermotoga maritima
1.11.1.25 37200
-
 calculated from sequence Thermotoga maritima
1.11.1.25 386000
-
 gel filtration Thermotoga maritima

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.25 Thermotoga maritima Q9WYL7
-
-
1.11.1.25 Thermotoga maritima Q9WZN7
-
-
1.11.1.25 Thermotoga maritima ATCC 43589 Q9WYL7
-
-
1.11.1.25 Thermotoga maritima ATCC 43589 Q9WZN7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.25 glutaredoxin + benzoquinone
-
 Thermotoga maritima glutaredoxin disulfide + H2O + hydroquinone
-
 ?
1.11.1.25 glutaredoxin + benzoquinone
-
 Thermotoga maritima ATCC 43589 glutaredoxin disulfide + H2O + hydroquinone
-
 ?
1.11.1.25 glutaredoxin 2 + H2O2
-
 Thermotoga maritima glutaredoxin 2 disulfide + 2 H2O
-
 ?
1.11.1.25 glutaredoxin 2 + H2O2
-
 Thermotoga maritima ATCC 43589 glutaredoxin 2 disulfide + 2 H2O
-
 ?
1.11.1.25 glutaredoxin 3 + H2O2
-
 Thermotoga maritima glutaredoxin 3 disulfide + 2 H2O
-
 ?
1.11.1.25 glutaredoxin 3 + H2O2
-
 Thermotoga maritima ATCC 43589 glutaredoxin 3 disulfide + 2 H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.11.1.25 decamer 10 * 37200, calculated from sequence Thermotoga maritima
1.11.1.25 dimer 2 * 17300, calculated fromm sequence Thermotoga maritima

Synonyms

EC Number Synonyms Comment Organism
1.11.1.25 TM0780
-
 Thermotoga maritima
1.11.1.25 TmPrxBCP
-
 Thermotoga maritima
1.11.1.25 TmPrxNtr
-
 Thermotoga maritima
1.11.1.25 TM_0386
-
 Thermotoga maritima

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.11.1.25 0.12
-
 H2O2 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 0.27
-
 H2O2 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 52.8
-
 benzoquinone pH and temperature not specified in the publication Thermotoga maritima

General Information

EC Number General Information Comment Organism
1.11.1.25 physiological function detoxification system, the enzyme prevents the damages caused by hydroperoxides Thermotoga maritima

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
1.11.1.25 3.1
-
 H2O2 pH and temperature not specified in the publication Thermotoga maritima
1.11.1.25 20.3
-
 H2O2 pH and temperature not specified in the publication Thermotoga maritima