BRENDA - Enzyme Database

Characterization of phosphatidic acid phosphatase activity in the oleaginous yeast Yarrowia lipolytica and its role in lipid biosynthesis

Hardman, D.; McFalls, D.; Fakas, S.; Yeast 34, 83-91 (2017)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
N-ethylmaleimide
potent inhibitor
Yarrowia lipolytica
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
cytosol
-
Yarrowia lipolytica
5829
-
3.1.3.4
membrane
-
Yarrowia lipolytica
16020
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.3.4
Mg2+
the enzyme activity of isoforms Pah1 and App1 increases 2.5fold with the addition of Mg2+ (1 mM)
Yarrowia lipolytica
3.1.3.4
additional information
the enzyme activities of isoforms Dpp1 and Lpp1 are independent from Mg2+
Yarrowia lipolytica
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.4
Yarrowia lipolytica
-
-
-
3.1.3.4
Yarrowia lipolytica Po1g
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
phosphatidic acid + H2O
-
752337
Yarrowia lipolytica
1,2-diacyl-sn-glycerol + phosphate
-
-
-
r
3.1.3.4
phosphatidic acid + H2O
-
752337
Yarrowia lipolytica Po1g
1,2-diacyl-sn-glycerol + phosphate
-
-
-
r
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
N-ethylmaleimide
potent inhibitor
Yarrowia lipolytica
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
cytosol
-
Yarrowia lipolytica
5829
-
3.1.3.4
membrane
-
Yarrowia lipolytica
16020
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.3.4
Mg2+
the enzyme activity of isoforms Pah1 and App1 increases 2.5fold with the addition of Mg2+ (1 mM)
Yarrowia lipolytica
3.1.3.4
additional information
the enzyme activities of isoforms Dpp1 and Lpp1 are independent from Mg2+
Yarrowia lipolytica
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
phosphatidic acid + H2O
-
752337
Yarrowia lipolytica
1,2-diacyl-sn-glycerol + phosphate
-
-
-
r
3.1.3.4
phosphatidic acid + H2O
-
752337
Yarrowia lipolytica Po1g
1,2-diacyl-sn-glycerol + phosphate
-
-
-
r
Expression
EC Number
Organism
Commentary
Expression
3.1.3.4
Yarrowia lipolytica
the enzyme activity is induced at the early exponential phase
up
Expression (protein specific)
EC Number
Organism
Commentary
Expression
3.1.3.4
Yarrowia lipolytica
the enzyme activity is induced at the early exponential phase
up