EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.4.41 | H49A | about 65% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | N68A | about 50% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | P43A | about 60% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | P43A/H49A | about 15% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | P43A/Y45A | about 15% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | T275A | about 80% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | Y45A | about 50% of wild-type activity | Arcanobacterium haemolyticum |
3.1.4.41 | Y45A/H49A | about 15% of wild-type activity | Arcanobacterium haemolyticum |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.41 | Arcanobacterium haemolyticum | C7SZ47 | - |
- |
3.1.4.41 | Arcanobacterium haemolyticum DSM 20595 | C7SZ47 | - |
- |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.1.4.41 | physiological function | the enzymatic activity of phospholipase D is necessary to promote hemolysis by arcanolysin, produced by the human pathogen Arcanobacterium haemolyticum. Incubating phospholipase D with erythrocytes corresponds with an increase in the amount of arcanolysin bound to host membranes | Arcanobacterium haemolyticum |