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Literature summary extracted from

  • Pollet, R.M.; DAgostino, E.H.; Walton, W.G.; Xu, Y.; Little, M.S.; Biernat, K.A.; Pellock, S.J.; Patterson, L.M.; Creekmore, B.C.; Isenberg, H.N.; Bahethi, R.R.; Bhatt, A.P.; Liu, J.; Gharaibeh, R.Z.; Redinbo, M.R.
    An atlas of beta-glucuronidases in the human intestinal microbiome (2017), Structure, 25, 967-977.e5 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.1.31
-
 Bacteroides fragilis
3.2.1.31
-
 Bacteroides ovatus
3.2.1.31
-
 Bacteroides uniformis
3.2.1.31
-
 Clostridium perfringens
3.2.1.31
-
 Streptococcus agalactiae
3.2.1.31
-
 Lachnospira eligens
3.2.1.31
-
 Parabacteroides merdae
3.2.1.31
-
 Phocaeicola dorei

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.31 Bacteroides fragilis
-
-
-
3.2.1.31 Bacteroides ovatus
-
-
-
3.2.1.31 Bacteroides uniformis
-
-
-
3.2.1.31 Clostridium perfringens Q8XP19
-
-
3.2.1.31 Clostridium perfringens 13 Q8XP19
-
-
3.2.1.31 Lachnospira eligens
-
-
-
3.2.1.31 Parabacteroides merdae
-
-
-
3.2.1.31 Phocaeicola dorei
-
-
-
3.2.1.31 Streptococcus agalactiae A0A0H1IHR6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.31
-
 Bacteroides fragilis
3.2.1.31
-
 Bacteroides ovatus
3.2.1.31
-
 Bacteroides uniformis
3.2.1.31
-
 Clostridium perfringens
3.2.1.31
-
 Streptococcus agalactiae
3.2.1.31
-
 Lachnospira eligens
3.2.1.31
-
 Parabacteroides merdae
3.2.1.31
-
 Phocaeicola dorei

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Bacteroides fragilis 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Bacteroides ovatus 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Bacteroides uniformis 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Clostridium perfringens 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Streptococcus agalactiae 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Lachnospira eligens 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Parabacteroides merdae 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Phocaeicola dorei 4-nitrophenol + beta-D-glucuronate
-
 ?
3.2.1.31 4-nitrophenyl beta-D-glucuronide + H2O
-
 Clostridium perfringens 13 4-nitrophenol + beta-D-glucuronate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.31 5
-
-
 Bacteroides fragilis
3.2.1.31 5
-
-
 Bacteroides ovatus
3.2.1.31 5.5
-
-
 Bacteroides uniformis
3.2.1.31 5.5
-
-
 Parabacteroides merdae
3.2.1.31 6
-
-
 Lachnospira eligens
3.2.1.31 6
-
-
 Phocaeicola dorei
3.2.1.31 6.5
-
-
 Lachnospira eligens
3.2.1.31 7.4
-
-
 Streptococcus agalactiae

General Information

EC Number General Information Comment Organism
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Bacteroides fragilis
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Bacteroides ovatus
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Bacteroides uniformis
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Clostridium perfringens
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Streptococcus agalactiae
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Lachnospira eligens
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Parabacteroides merdae
3.2.1.31 metabolism microbiome-encoded beta-glucuronidase enzymes play important roles in human health by metabolizing drugs in the gastrointestinal tract Phocaeicola dorei