EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.7.7.101 | structures of the DnaG catalytic core bound to metal ion cofactors and either individual nucleoside triphosphates or the nucleotidyl alarmones, pppGpp and ppGpp | Staphylococcus aureus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.101 | ppGpp | inhibitory, impedes primase activity by blocking entry of an incoming NTP, and interfering with the binding of either an initiating 5'-NTP, or the extensible 3'-end of an RNA-DNA heteroduplex | Escherichia coli | |
2.7.7.101 | ppGpp | inhibitory, impedes primase activity by blocking entry of an incoming NTP, and interfering with the binding of either an initiating 5'-NTP, or the extensible 3'-end of an RNA-DNA heteroduplex | Staphylococcus aureus | |
2.7.7.101 | pppGpp | inhibitory, impedes primase activity by blocking entry of an incoming NTP, and interfering with the binding of either an initiating 5'-NTP, or the extensible 3'-end of an RNA-DNA heteroduplex | Escherichia coli | |
2.7.7.101 | pppGpp | inhibitory, impedes primase activity by blocking entry of an incoming NTP, and interfering with the binding of either an initiating 5'-NTP, or the extensible 3'-end of an RNA-DNA heteroduplex | Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.101 | Escherichia coli | P0ABS5 | - |
- |
2.7.7.101 | Staphylococcus aureus | O05338 | - |
- |