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Literature summary extracted from
- Lipoprotein lipase activity does not predict very low-density lipoprotein-triglyceride fatty acid oxidation during exercise (2017), Scand. J. Med. Sci. Sports, 27, 474-481 .
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.34 | triacylglycerol + H2O | Homo sapiens | - |
diacylglycerol + a carboxylate | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.34 | Homo sapiens | P06858 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.34 | triacylglycerol + H2O | - |
Homo sapiens | diacylglycerol + a carboxylate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | LPL | - |
Homo sapiens |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | physiological function | lipoprotein lipase (LPL) is a key enzyme in facilitating fatty acid uptake from lipoproteins. Very low-density lipoprotein-triglyceride (VLDL-TG) is a quantitative important substrate for lipid oxidation contributing with 10-20% to total energy expenditure, but only 3-6% during exercise despite an increase in total lipid oxidation. VLDL-TG storage is measured in adipose tissue biopsies. Exercise does not affect muscle LPL activity. No association is observed between muscle LPL activity and VLDL-TG oxidation, neither in the basal state nor during exercise. Exercise does not affect upper body or lower body adipose tissue LPL activity. The basal adipose tissue fractional VLDL-TG storage is not associated with upper body or lower body subcutaneous adipose tissue LPL activity. Muscle LPL activity does not predict VLDL-TG oxidation during rest or exercise. In addition, adipose tissue LPL activity is not associated with VLDL-TG storage | Homo sapiens |
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Release 2023.1 (January 2023)
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