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Literature summary extracted from

  • Zhang, J.; Yu, Y.C.; Yeh, J.T.; Hwang, T.C.
    Functional characterization reveals that zebrafish CFTR prefers to occupy closed channel conformations (2018), PLoS ONE, 13, e0209862 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.6 expressed in CHO cells Danio rerio

Protein Variants

EC Number Protein Variants Comment Organism
5.6.1.6 E1372Q the mutation abolishes the ATPase activity of the enzyme Danio rerio

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.6 ATP + H2O + closed Cl- channel Danio rerio
-
 ADP + phosphate + open Cl- channel
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.6 Danio rerio
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
5.6.1.6 phosphoprotein the enzyme is activated by protein kinase A-dependent phosphorylation Danio rerio

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.6 ATP + H2O + closed Cl- channel
-
 Danio rerio ADP + phosphate + open Cl- channel
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.6 CFTR
-
 Danio rerio
5.6.1.6 cystic fibrosis transmembrane conductance regulator
-
 Danio rerio