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Literature summary extracted from

  • Szatmari, D.; Bugyi, B.; Ujfalusi, Z.; Grama, L.; Dudas, R.; Nyitrai, M.
    Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin (2017), PLoS ONE, 12, e0186288 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.6.1.8 actin
-
 Rattus norvegicus
5.6.1.8 leiomodin2 upon its interaction with the filaments leiomodin2 decreases the actin-activated Mg2+-ATPase activity of skeletal muscle myosin Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.6.1.8 Mg2+ required for activity Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.8 ATP + H2O + myosin bound to actin filament at position n Rattus norvegicus
-
 ADP + phosphate + myosin bound to actin filament at position n+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.8 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.8 skeletal muscle
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.8 ATP + H2O + myosin bound to actin filament at position n
-
 Rattus norvegicus ADP + phosphate + myosin bound to actin filament at position n+1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.8 heavy meromyosin truncated form of skeletal muscle myosin Rattus norvegicus
5.6.1.8 HMM
-
 Rattus norvegicus