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Literature summary extracted from
- Myosin phosphatase fine-tunes zebrafish motoneuron position during axonogenesis (2016), PLoS Genet., 12, e1006440 .
No PubMed abstract available
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.53 | Danio rerio | Z4YIS0 | protein phosphatase 1 regulatory subunit 12A | - |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.1.3.53 | physiological function | as motor axons exit from the spinal cord and extend through extracellular matrix produced by adjacent notochord cells,these cells shift several cell diameters caudally. Individual motoneuron cell bodies stay aligned with their extending axons. This alignment requires myosin phosphatase activity within motoneurons, and mutations in the myosin phosphatase subunit Mypt1 increase myosin phosphorylation causing a displacement between motoneuron cell bodies and their axons | Danio rerio |
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Release 2023.1 (January 2023)
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