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Literature summary extracted from

  • Kai, K.; Mizutani, M.; Kawamura, N.; Yamamoto, R.; Tamai, M.; Yamaguchi, H.; Sakata, K.; Shimizu, B.
    Scopoletin is biosynthesized via ortho-hydroxylation of feruloyl CoA by a 2-oxoglutarate-dependent dioxygenase in Arabidopsis thaliana (2008), Plant J., 55, 989-999 .
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.11.61 0.036
-
 trans-feruloyl-CoA 30°C, pH 6.5 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.61 additional information Arabidopsis thaliana trace reactions with p-coumaroyl CoA, no substrate: ferulic acid, feruloylquinic acid, caffeic acid, caffeoyl CoA, p-coumaric acid, cinnamic acid, cinnamoyl CoA, benzoyl CoA ?
-
 ?
1.14.11.61 trans-feruloyl-CoA + 2-oxoglutarate + O2 Arabidopsis thaliana
-
 trans-6-hydroxyferuloyl-CoA + succinate + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.61 Arabidopsis thaliana Q9LHN8
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.11.61 root
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.61 additional information trace reactions with p-coumaroyl CoA, no substrate: ferulic acid, feruloylquinic acid, caffeic acid, caffeoyl CoA, p-coumaric acid, cinnamic acid, cinnamoyl CoA, benzoyl CoA Arabidopsis thaliana ?
-
 ?
1.14.11.61 trans-feruloyl-CoA + 2-oxoglutarate + O2
-
 Arabidopsis thaliana trans-6-hydroxyferuloyl-CoA + succinate + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.61 feruloyl CoA ortho-hydroxylase 1
-
 Arabidopsis thaliana

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.14.11.61 11
-
 trans-feruloyl-CoA 30°C, pH 6.5 Arabidopsis thaliana

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.11.61 6.5
-
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
1.14.11.61 physiological function T-DNA insertion mutants of F6'H1 show severe reductions in scopoletin and scopolin levels in the roots. The pattern of F6'H1 expression is consistent with the patterns of scopoletin and scopolin accumulation Arabidopsis thaliana